ABSTRACT

We report a case in whom back pain associated with vertebral compressions and collapse were presenting features of childhood acute lymphoblastic leukemia (ALL); radiological remodeling with return of function occurred with remission. This report is intended to promote greater awareness that acute leukemia can cause significant back pain in children without other systemic symptoms.

There should be a high index of suspicion in patients, particularly if there is worsening back pain with the associated radiographic findings of vertebral compression fractures. Antileukemic treatment usually results in rapid symptomatic relief as well as radiographic evidence of bony remodeling.