E-ISSN: 2147-5903
DEGENERATIVE DISC DISEASE AND GENETIC
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VOLUME: 26 ISSUE: 1
P: 67-78
January 2015

DEGENERATIVE DISC DISEASE AND GENETIC

J Turk Spinal Surg 2015;26(1):67-78
Ramazan KAHVECI 1
Hüseyin ÖZEVREN 2
Ergün KARAVELIOĞLU 3
1. M.D., Department of Neurosurgery, Private Polatlı Can Hospital, Ankara, Turkey
2. M.D., Department of Neurosurgery, Dicle University, School of Medicine, Diyarbakır, Turkey
3. M.D., Department of Neurosurgery, Afyon Kocatepe University, School of Medicine, Afyon, Turkey
No information available.
No information available
Received Date: 01.11.2014
Accepted Date: 11.12.2014
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ABSTRACT

Although development of the intervertebral disc disease is a multifactorial condition, recent studies associated with genes playing a role in disc dejeneration revealed that the importance of the genetic factors in the development of disc disease. Our purpose of this study is to review current knowledge on genes associated with intervertebral disc degeneration.

Keywords:
degenerative disc disease, aggrecan, collagene, vitamin D receptor, interleukin, ADAMTS, matrixmetalloproteinase