DEGENERATIVE DISC DISEASE AND GENETIC
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DEGENERATIVE DISC DISEASE AND GENETIC

J Turk Spinal Surg 2015;26(1):67-78
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Abstract

Although development of the intervertebral disc disease is a multifactorial condition, recent studies associated with genes playing a role in disc dejeneration revealed that the importance of the genetic factors in the development of disc disease. Our purpose of this study is to review current knowledge on genes associated with intervertebral disc degeneration.

Keywords: degenerative disc disease, aggrecan, collagene, vitamin D receptor, interleukin, ADAMTS, matrixmetalloproteinase